学术沙龙

学术沙龙第三十五期:在活体单细胞中构建一个实时可视化的TOR激酶活性检测系统

发布时间:2023-05-09  阅读次数:1406

报 告 人:付力文   农生学院植物科学系 长聘教轨副教授 博导 独立PI

时    间:2023年5月10日 (星期三) 12:40-14:00

地    点:农生学院创新楼(B楼)104会议室

主办单位:农生学院学科与科技办、农生学院青年教师联谊会

报告题目:在活体单细胞中构建一个实时可视化的TOR激酶活性检测系统

报告摘要:

TOR (Target of Rapamycin)激酶是植物信号转导网络中的核心调控元件。但是,由于TOR激酶自身的一些特点,在植物中检测TOR激酶活性非常困难。目前我们正在尝试在植物活体单细胞系统中建立检测TOR激酶活性的手段。本次报告将为大家分享相关研究进展,并为大家介绍一下我们在番茄中对于TOR激酶信号转导网络的一些初步研究。

报告人简介:

【PI学科组研究方向】

植物进化出了复杂的信号转导网络以应对外部环境变化。TOR (Target of Rapamycin)激酶是植物信号转导网络中的核心调控元件。目前实验室以番茄为模式植物,综合运用蛋白质组学、生物化学以及分子生物手段研究不同外界信号(营养、激素、逆境等等)如何通过TOR激酶调控番茄的生长、发育和胁迫响应。

【代表性著作】

  1. Liwen Fu#, Yanlin Liu#, Guochen Qin, Ping Wu, Hailing Zi, Zhongtian Xu, Xiaodi Zhao, Yue Wang, Yaxing Li, Shuhui Yang, Chao Peng, Catherine C. L. Wong, Sang-Dong Yoo, Zecheng Zuo, Renyi Liu, Young-Hee Cho and Yan Xiong. (2021) The TOR-EIN2 axis mediates nuclear signalling to modulate plant growth. Nature, 591 (7849): 288-292 (#共同第一作者)
  2. Liwen Fu, Pengcheng Wang, and Yan Xiong. (2020) Target of rapamycin signaling in plant stress responses. Plant Physiology, 182: 1613-1623.

 

ACADEMIC SALON (XXXV)

SPEAKER: Liwen Fu

Tenure-track Associate Professor, Ph.D. Supervisor, PI

Department of Plant Science, SAB

TIME :12:40-14:00  May 10th, 2023  (Wed)

VENUE:Room 104, Building B, SAB

ORGANIZER:Office of Discipline and Science & Technology, SAB; 

Young Teachers Association, SAB

TITLE:Constructing a real-time visualizable system for monitoring the activity of TOR kinase in living single cells

ABSTRACT: 

TOR (Target of Rapamycin) kinase is a central regulator in plant signal transduction network. However, it is extremely difficult to test TOR activity in plants. We are now constructing a visualizable system to monitor TOR activity in living single cells in plants. In this lecture, I will share some research progresses in this project. Meanwhile, I will also introduce to you some preliminary research on tomato TOR kinase carried out in our lab. 

 

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